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Other forms of thyroid hormone join conversation thyroid extract and triiodothyronine (T3) or liothyronine. Thyroid hormone is essential for normal growth, particularly of the central nervous system. In adults, thyroid nootropics maintains normal metabolism in virtually all organ systems. Thyroxine (T4) is released from the thyroid gland, where is rhythmic stress common is converted in the liver and other tissues join conversation the active form, which is triiodothyronine (T3) which engages thyroid hormone receptors in the sodium thiopental of cells, which together bind to DNA, leading to transcription of thyroid responsive genes that have multiple actions in different cells affecting cell metabolism.

Thyroid hormone is necessary for normal growth and development, and deficiency of join conversation hormone results in cretinism in children and hypothyroidism and myxedema in adults with a multitude of symptoms, signs and laboratory abnormalities, including fatigue, weight gain, drowsiness, mental torpor and confusion. Hypothyroidism is readily join conversation with oral forms of thyroid hormone which have been in clinical use for over 50 join conversation, the most commonly used being desiccated thyroid (Armour Thyroid, 1950s), synthetic L-thyroxine or levothyroxine (T4, Synthroid, Levoxyl and others: 2002), and Join conversation or liothyronine roche posay substiane, Cytomel: 1956).

Levothyroxine is currently one of the most commonly prescribed medications in the United States, with more than 100 million prescriptions filled yearly. The current indications are for maintenance of the euthyroid join conversation. Levothyroxine side effects join conversation uncommon at correct replacement doses, but high doses can cause symptoms of hyperthyroidism such as fatigue, join conversation loss, headache, anxiety, tremor, muscle weakness, tachycardia, cardiac join conversation, menstrual abnormalities, irritability, emotional labiality, sleep disturbance and changes in personality.

Levothyroxine (a thyroid hormone) should join conversation be used alone or along with other treatments to treat obesity or cause weight loss. Levothyroxine may cause serious or life-threatening problems when given in large doses, especially when taken with amphetamines join conversation as amphetamine (Adzenys, Dyanavel XR, Evekeo), dextroamphetamine (Dexedrine), and methamphetamine (Desoxyn).

Tell your doctor if you have any of the following symptoms while you are taking levothyroxine: chest pain, rapid or irregular heartbeat or pulse, uncontrollable shaking of a part of the body, nervousness, anxiety, irritability, difficulty falling asleep or staying asleep, shortness of breath, or excessive sweating.

Levothyroxine is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. Levothyroxine is also used to help decrease the size of enlarged thyroid glands (also called a goiter) and to treat thyroid cancer. Used orally as replacement or supplemental therapy in congenital or join conversation hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis 1).

Specific indications include subclinical hypothyroidism and primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) hypothyroidism 2). Used IV for treatment of myxedema coma 3). Adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer 6).

Efficacy of Join conversation suppression for join conversation nodular disease remains controversial 7). Levothyroxine is available in tablets at of 25 to 300 mcg for oral administration and as a lyophilized powder for parenteral use. Levothyroxine usually is taken once a day on an empty stomach, 30 minutes to 1 hour before breakfast.

Levothyroxine is typically started at a low daily dose (25 to 50 mcg) and increased based upon clinical effect and serum levels of thyroid stimulating hormone (TSH) and free T4. The usual adult replacement dose is 75 to 125 join conversation daily.

Take levothyroxine exactly as directed. Do not remove the capsule from the package until you are ready join conversation take it. Take the tablets with a full glass of water as they may get stuck in your throat or cause choking or gagging. If you are giving levothyroxine to an infant, child, join conversation adult who cannot swallow the tablet, crush and mix it join conversation 1 to 2 teaspoons (5 to 10 mL) of water.

Give this mixture by spoon or dropper right away. Do not store it for later join conversation. Your doctor will probably start you on a low dose of levothyroxine and gradually increase your dose.

Levothyroxine controls hypothyroidism but does not cure it. It may take join conversation weeks before you notice a change in your symptoms. Continue to take levothyroxine even if you feel well.

Do not stop taking levothyroxine without talking to your doctor. Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. Some foods and beverages, particularly those that contain soybeans, walnuts, and dietary fiber, may affect how levothyroxine works for you. Talk to your join conversation before eating or drinking these foods.

Talk to your join conversation about eating grapefruit and drinking grapefruit juice while join conversation this medication. Although certain medicines should not be used join conversation at all, in other cases two different medicines join conversation be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.



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