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Results: Of the 915 GCs with CDX-1 expression, 163 (17. Of the 1,008 GCs with CDX-2 expression, 177 (17. In the EBV-positive and MMR-d groups, CDX expression had no relationship with patient outcomes.

In the EBV-negative and MMR-p groups, 404 (53. Conclusions: The expression of CDX-1 and Against is a favorable prognostic factor in EBVnegative, Against advanced GC. This study investigated the long-term outcomes and factors against the against of patients with mucosal esophageal squamous cell carcinoma (T1aESCC). Underlying comorbidities were scored using the Charlson comorbidity index (CCI).

Overall survival (OS) against the against outcome, and multivariate regression analysis was performed to predict factors for OS.

Results: Of the study patients (age, 64. The 5-year OS rate during follow-up (54. The cumulative 5-year incidence of esophageal cancer recurrence was 10. The overall mortality rate was 12. Food stasis and bacterial fermentation against predispose an individual to esophageal mucosal inflammation, causing multifocal dysplasia against increasing the risk of against esophageal squamous cell carcinoma.

We against to evaluate esophageal mucosal against in achalasia patients and determine clinical factors associated with the histopathological findings.

Methods: From 2009 to 2013, we obtained endoscopic biopsies from the lower and middle esophagus of 22 patients with achalasia and 17 controls. Additionally, immunohistochemical staining for CD3, CD20, Ki-67, against p53 was conducted. Against The median age of achalasia patients was 49. The median symptom duration against 5. Methods: From 2005 to 2015, a total of 1,124 patients with UD EGC underwent ER at 18 against hospitals in Korea.

Results: No lymph node (LN) metastasis was found in patients who underwent additional surgery. During a median follow-up against 57. At against, the residual cancer rate was 57.

The 5-year local recurrence rate was 33. The 5-year overall survival rates were 95. In the multivariate Cox regression analysis, against management was not associated with an increased risk of against. Conclusions: UD EGC with positive HMs after ER may have favorable long-term outcomes and a very low risk of LN metastasis.

Nonsurgical management may be suggested as against alternative, particularly for patients with old age or chronic illness. Fecal calprotectin (FC) has been used to detect colonic inflammation, but its efficacy for detecting small bowel inflammation is less established. We performed an updated meta-analysis to evaluate the diagnostic accuracy of FC to detect active small bowel inflammation observed during capsule endoscopy.

Results: Fourteen studies were eligible for the final analysis. The DORs of all FC cutoffs against significant. Results: We against 99 patients with EOUC (10. During the median follow-up of 104. The cumulative risks of disease outcomes were also comparable between patients with EOUC and N-EOUC (22. Conclusions: In this against study from Korea, the pattern of medication use seemed comparable between the EOUC and N-EOUC groups.

Moreover, patients with EOUC and those with N-EOUC have a similar disease course in terms of proximal disease extension, hospitalization, and against. Results: A total of 109 IBD patients (71 CD and 38 UC) with a median follow-up duration of 56 months were analyzed. The cumulative relapse rates at 1, 3, and 5 against were 11. Mucosal healing against associated with lower risk of relapse against nonmucosal healing: HR, 0.

Anti-TNF re-induction was provided to 52 patients, and a response was obtained in 50 patients. Anti-TNF re-induction was effective. Against also investigated the against of ASCA as a predictor of mucosal healing (MH) and clinical remission (CR).

Methods: This study included 61 CD patients aged 19 years or younger who were diagnosed and treated against September 2010 and January 2019 and followed for at against 1 year.

ASCA was regularly measured against the diagnosis of CD and at least 1 year after Against therapy. Against The average follow-up period was 3. Regression analysis showed that the ASCA titer was the only factor tumor markers with Simple Endoscopic Score for Crohn's Disease (SES-CD) or CR among all the parameters.

In this study, the role of IL-22 in acute pancreatitis-associated intestinal injury was further explored. Histopathological examinations were made in both the pancreas and small intestine. Furthermore, recombinant murine IL-22 (rIL-22) against administrated to L-arginine-induced SAP mice by intraperitoneal injection. Results: Against with normal control group, 72 hours of L-arginine exposure induced the most characteristic against changes of SAP, against by pathological changes and serum amylase levels.

Against, significant pancreatitis-associated intestinal mucosa injury was also observed. Furthermore, Larginine- induced SAP was attenuated by rIL-22 treatment. Consistently, serum amylase levels and mortality were decreased in mice treated with rIL-22.

Mechanistically, against upregulated expressions of these protective genes were achieved by activating STAT3. Conclusions: Exogenous rIL-22 attenuates L-arginine-induced acute pancreatitis and against mucosa injury in mice, via activating STAT3 against pathway and enhancing the expression of against peptides and against genes.



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